Pennsylvania Sun news

Oakland burglary suspect caught after police search

A man who's suspected of burglarizing an Oakland home was in custody early Wednesday after a search that involved dozens of police officers canvassing the neighborhood and a hillside near the Parkway ...
Crash On Blue Route In Springfield Has Northbound Traffic At A Standstill

SPRINGFIELD - A three-vehicle crash on I-476 has traffic tied up in both directions.The crash occurred at about 6:30 a.m. at the entrance ramp to northbound I-476 in Springfield. There are injuries reported, the extent of which are currently unkown.Northbound traffic is at a standstill. Southbound traffic is also experiencing delays. Alternate routes, such as Route 320, also have heavy ...
Police Paraplegic castrated at Philly facility man charged

PHILADELPHIA (AP) - A 41-year-old man is being held on $5 million bail after police say he castrated a paraplegic during a dispute at an assisted living facility in Philadelphia.Authorities say Edgar Bonilla is charged with attempted murder, aggravated assault and other counts in Monday night's attack inside the Inglis Apartments at Elmwood. Lt. John Walker says Bonilla was visiting a ...
Corbett plan to fix pension problem stalls in Senate

HARRISBURG, Pa. (AP) - Gov. Tom Corbett's plan to slash $12 billion from future public employee pension benefits appears dead in the Republican-controlled state Senate.Senate Majority Leader Dominic Pileggi said the Finance Committee will meet Wednesday to amend Corbett's pension bill. It plans to advance a portion of the bill that would shift future hires into a 401K-style plan, ...
Top Pa. senator Liquor bill still lacks support

By MARC LEVY,Associated Press HARRISBURG, Pa. (AP) - Top Republican state senators continued to seek enough support Tuesday to pass legislation one of their members is writing to liberalize wine, beer and liquor sales in Pennsylvania and give Gov. Tom Corbett the ability to claim victory on one of his top priorities.However, legislation being written by Bucks County Sen. Charles McIlhinney ...

Movie Review

The Family Stone

In the entire 100 minutes of Thomas Bezuchas family-tension dramedy The Family Stone, there are approximately 5 minutes that are fundamentally believable. The rest of the film is contrived, often ridiculous, sometimes sappy, and always annoyingly self-congratulatory. Virtually eve ... ...

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Saudi Archeological Relics Exhibition in Pennsylvania USA starts on Friday 21 June 2013

Pennsylvania, USA: June 19 -- (BNA)-- The Saudi Commission for Tourism and Antiquities (SCTA)'s President, HRH Prince Sultan bin Salman bin Abdulaziz; and, Governor of U.S. Pennsylvania State, Mr. Tom Corbett, are slated to co-inaugurate next week (on Friday, June, 21, 2013) an exhibition themed (Saudi Archeological Masterpieces Throughout the Ages', according to the sisterly Saudi ...
Police Vandals damage Pa. church with syrup

POTTSTOWN, Pa. (AP) -- Police are searching whoever vandalized a Philadelphia-area church with syrup and fire extinguishers before taking off with a bottle of ...
Allentown council to vote on clean air ordinance

ALLENTOWN, Pa. (AP) -- The city council in Allentown is set to vote on a clean air ordinance that would include round-the-clock monitoring of any new waste-to-energy plants built ...
Giant bee swarm removed from eastern Pa. building

Yes, the eastern Pennsylvania community was abuzz about what could have been a sticky situation outside the Lipkin Technology Building on Tuesday. The Republican Herald reports ...
Munhall manager resigns citing ‘disillusionment’

Councilman Dan Lloyd said Galla "gave lots of reasons" for resigning and the resignation letter reads as follows: "Although my time with the borough of Munhall has been, for the most part, satisfying and productive, for quite a while now I have become disillusioned, disenfranchised and less and less satisfied with my current work situation. Attempts at resolution have been ...

More Pennsylvania Sun news

Making headlines

Our nuclear programmes are completely transparent. But we are ready to show greater transparency and make clear for the whole world that the steps of the Islamic Republic of Iran are completely within international frameworks. The sanctions are unfair, the Iranian people are suffering, and our (nuclear) activities are legal. These sanctions are illegal and only benefit Israel.

Hassan Rouhani

Iran's president-elect was speaking after his historic election victory.

Hotel Review

Beach Rotana Hotel & Towers

I could not find the Web site for this hotel, and it was not listed on any of the Internet ...

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Featured Story

Protein key to breast cancer recurrence identified

Researchers at the Perelman School of Medicine, University of Pennsylvania have identified a key molecular player in recurrent breast cancer - a finding that suggests potential new therapeutic strategies.

The study, performed in the laboratory of Lewis A. Chodosh MD, PhD, chair of Cancer Biology and director of Cancer Genetics at the Abramson Family Cancer Research Institute, implicates the tumor suppressor protein Par-4 in recurrent breast cancer.

Par-4 is downregulated in recurrent tumors, and knocking the gene's expression down accelerates tumor recurrence in a mouse model of recurrent breast cancer. Conversely, overexpressing Par-4 delays the onset of tumor recurrence.

Data from human breast cancer patients confirm these findings. The authors analyzed patient tumors from the I-SPY 1 TRIAL, a clinical trial that measured tumor gene expression patterns and response to neoadjuvant chemotherapy.

They found that Par-4 expression is low in "residual disease" (that portion of a tumor that survives chemotherapy) compared to the primary tumor prior to treatment, and that women with low Par-4 levels in their primary tumors tend to respond less well to treatment and are more likely to experience a relapse. ...