Pennsylvania Sun news

Police Paraplegic castrated at Philly facility

PHILADELPHIA -; A 41-year-old man is being held on $5 million bail after police say he castrated a paraplegic during a dispute at an assisted living facility in ...
Lil Red puts a modern musical spin on a classic tale Pittsburgh Tribune-Review

"Li'l Red" is not exactly the Brothers Grimm's storybook version of "Little Red Riding Hood." In Richard Kinter's modern adaptation of the classic fairytale, which opens the summer season for Johnny Appleseed Children's Theatre at Apple Hill Playhouse, the wolf that frightened the little girl on her way to see her grandma is more "cool dude" than ...
Middletown pediatrician held for trial in shooting of former partner

Lauren Daly is walked out of the Pennsylvania State Police barracks after her arrest in shooting of her former partner. Times staff / JULIA WILKINSON MIDDLETOWN - Lauren Patricia Daly, the 41-year-old pediatrician charged with shooting her former domestic partner on Memorial Day, was held over for trial Tuesday after a preliminary hearing in Lima District Court.At the request of Delaware ...
10 things you need to know for Wednesday

C-City Blogger Presenting Chester City's news and views to Delco Times web visitors who want to know more of what's going on in the City besides the stories they read in the ...
SEPTA claims huge win for U.S. Open services

Crowds get off SEPTA's Route 100 line at the Ardmore Avenue station as commuters pour in to watch the U.S. Open at Merion Golf Club. The tournament proved to be a big win for mass transit. (Special to the Times/Pete Bannan) While it was a busy week for workers and volunteers who helped make the U.S. Open operational, it was also a busy week for transportation services that moved fans ...

Movie Review

The Family Stone

In the entire 100 minutes of Thomas Bezuchas family-tension dramedy The Family Stone, there are approximately 5 minutes that are fundamentally believable. The rest of the film is contrived, often ridiculous, sometimes sappy, and always annoyingly self-congratulatory. Virtually eve ... ...

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Toby Farms Intermediate students learn about bullying

The Mission and Making a Change Group, both Chester grassroots organizations, recently hosted an anti-bullying assembly at Toby Farms Intermediate School featuring representatives from the Pennsylvania State Police and the FBI.Each student received a backpack and brochures with anti-bullying information. More than 350 students in grades 4-8 participated.Darren Laws, founder of the Mission, said ...
Tinicum OKs bid for building demolition

TINICUM - Commissioners voted unanimously Monday to approve a bid by Ridley Excavating to raze a building at 347 N. Governor Printz Blvd., which the township purchased earlier this year and plans to maintain as open space.Ridley Excavating bid $14,800 for the work.- LAURA ...
Penn State lacrosse Lions raise money for Wounded Warriors

UNIVERSITY PARK - Penn State’s men’s lacrosse team recently donated $2,940 to the Wounded Warrior Project.The Nittany Lions, who finished last season 12-5, teamed with Penn State Ability Athletics head coach Teri Jordan to raise the money through T-shirt sales and submit the ...
Penn State student football tickets on sale Monday

UNIVERSITY PARK - Penn State student football season tickets go on sale Monday.More than 21,000 student full-season tickets will be available for the coming season, which kicks off the home schedule against Eastern Michigan on Sept. 7.Complete instructions for students are available ...
Lawsuit to cost Union Township upward of $49000

Union Township taxpayers will be on the hook for the more than $49,000 in costs after losing the lawsuit brought by Citizen’s Hook and Ladder fire company in Milesburg to recover three years’ worth of funding. But just how and when the taxpayers will have to come up with the money is being worked out by the township’s supervisors.The cost from the lawsuit — the amount the ...

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Making headlines

Our nuclear programmes are completely transparent. But we are ready to show greater transparency and make clear for the whole world that the steps of the Islamic Republic of Iran are completely within international frameworks. The sanctions are unfair, the Iranian people are suffering, and our (nuclear) activities are legal. These sanctions are illegal and only benefit Israel.

Hassan Rouhani

Iran's president-elect was speaking after his historic election victory.

Hotel Review

Beach Rotana Hotel & Towers

I could not find the Web site for this hotel, and it was not listed on any of the Internet ...

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Should tax havens be forced to lift their shroud of secrecy?

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Featured Story

Protein key to breast cancer recurrence identified

Researchers at the Perelman School of Medicine, University of Pennsylvania have identified a key molecular player in recurrent breast cancer - a finding that suggests potential new therapeutic strategies.

The study, performed in the laboratory of Lewis A. Chodosh MD, PhD, chair of Cancer Biology and director of Cancer Genetics at the Abramson Family Cancer Research Institute, implicates the tumor suppressor protein Par-4 in recurrent breast cancer.

Par-4 is downregulated in recurrent tumors, and knocking the gene's expression down accelerates tumor recurrence in a mouse model of recurrent breast cancer. Conversely, overexpressing Par-4 delays the onset of tumor recurrence.

Data from human breast cancer patients confirm these findings. The authors analyzed patient tumors from the I-SPY 1 TRIAL, a clinical trial that measured tumor gene expression patterns and response to neoadjuvant chemotherapy.

They found that Par-4 expression is low in "residual disease" (that portion of a tumor that survives chemotherapy) compared to the primary tumor prior to treatment, and that women with low Par-4 levels in their primary tumors tend to respond less well to treatment and are more likely to experience a relapse. ...