Pennsylvania Sun news

Oly sprinter Campbell-Brown suspended amid probe

KINGSTON, Jamaica - Veronica Campbell-Brown's agent insists one of the cornerstones of Jamaica's wide-ranging sprint success "is not a cheat," even though the test results disagree.While her case is being decided, the three-time Olympic gold medalist will sit out and her country will try to make sense of one of its longest-held fears: a high-profile track star getting busted ...
Revere securing hold on Phils leadoff spot

Email PHILADELPHIA -- Nine days ago, Ben Revere was hitting .244. Eight games and 16 hits later, his season average was up to .274 heading into Tuesday's game against Washington. Revere hit safely in each of those eight games and was 16-for-37 (.432) in that span. The center fielder has four multi-hit games in those contests, including a two-hit performance in the series opener against the ...
Philly man finds sinkhole filled with green ooze

Steven Reitz said Tuesday that the sinkhole opened in the Northern Liberties section of the city last week and the ooze appeared several days later. He said when he and some friends spotted the green pool, they didn't know what to make of ...
Cross-state turnpike trip likely to hit $50 by 2021

The cash toll for a cross-state trip on the Pennsylvania Turnpike is expected to reach about $50 by 2021, state Auditor General Eugene DePasquale said Tuesday as he urged lawmakers to halt the spiraling debt resulting from the massive contributions the turnpike is required to make toward the state's other transportation ...
Federal judge frees Geneva College from government requirement on health coverage

A federal judge on Tuesday temporarily blocked the government from requiring a private college in Beaver County to include coverage for abortifacients in the health insurance plan for its ...

Movie Review

Reservoir Dogs

"Reservoir Dogs," the exhilarating debut film of 29-year old writer/director Quentin Tarantino, is a ballet of macho posturing, gun-pointing, and the creative uses of every four-letter word imaginable. Its testosterone level is off every chart, and it happily wallows in its own juvenile love of criminals, violence, and vulgarity. Taking a note from Sam Peckinpah, Tarantino populated his film with ... ...

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Pittsburgh’s Schwartz’s is reborn as a Living Market on the South Side

'We're linking the urban and suburban 'Food Not Lawns' movement with the urban core and our inner core, our inner health,' says Elisa Haransky-Beck, of Monroeville, of transforming the South Side's Schwartz's Market, which was once a mainstay grocery, into a food and art market. Mr. Beck's grandparents were Morris and Helen Schwartz, who moved their ...
No.1 draft pick signs with Pirates

THE PIRATES -- ONE OF THEIR FIRST ROUND DRAFT PICKS! REESE McGUIRE TURNS DOWN A SCHOLARSHIP TO THE UNIVERSITY OF SAN DIEGO TO BECOME A BUCCO. ACTION SPORTS GUY JUNKER -- CATCHING U TODAY WITH THE CATCHER OF TOMORROW! 3 3 3 ...
Okla. executes inmate convicted of killing couple

McALESTER, Okla. -- Oklahoma executed a 36-year-old man on Tuesday for the October 2000 stabbing deaths of a couple on whose ranch he had worked.James Lewis DeRosa was killed by lethal injection at the Oklahoma State Penitentiary in McAlester. He was the second inmate the state executed this year.Prosecutors say DeRosa and an accomplice, 33-year-old John Eric Castleberry, went to Curtis and ...
Ortiz Red Sox top Rays in rainy twinbill opener

Boston Red Sox's David Ortiz jogs off the field during a rain delay in the fifth inning of the first baseball game of a doubleheader against the Tampa Bay Rays in Boston, Tuesday, June 18, ...
Pa. Senate OKs bill to expand DNA tests in crimes

HARRISBURG, Pa. (AP) -- A bill to require DNA testing of suspects accused of certain crimes in Pennsylvania is headed to the state House of Representatives for the second time in two ...

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Making headlines

Our nuclear programmes are completely transparent. But we are ready to show greater transparency and make clear for the whole world that the steps of the Islamic Republic of Iran are completely within international frameworks. The sanctions are unfair, the Iranian people are suffering, and our (nuclear) activities are legal. These sanctions are illegal and only benefit Israel.

Hassan Rouhani

Iran's president-elect was speaking after his historic election victory.

Hotel Review

Beach Rotana Hotel & Towers

I could not find the Web site for this hotel, and it was not listed on any of the Internet ...

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Should tax havens be forced to lift their shroud of secrecy?

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Featured Story

Protein key to breast cancer recurrence identified

Researchers at the Perelman School of Medicine, University of Pennsylvania have identified a key molecular player in recurrent breast cancer - a finding that suggests potential new therapeutic strategies.

The study, performed in the laboratory of Lewis A. Chodosh MD, PhD, chair of Cancer Biology and director of Cancer Genetics at the Abramson Family Cancer Research Institute, implicates the tumor suppressor protein Par-4 in recurrent breast cancer.

Par-4 is downregulated in recurrent tumors, and knocking the gene's expression down accelerates tumor recurrence in a mouse model of recurrent breast cancer. Conversely, overexpressing Par-4 delays the onset of tumor recurrence.

Data from human breast cancer patients confirm these findings. The authors analyzed patient tumors from the I-SPY 1 TRIAL, a clinical trial that measured tumor gene expression patterns and response to neoadjuvant chemotherapy.

They found that Par-4 expression is low in "residual disease" (that portion of a tumor that survives chemotherapy) compared to the primary tumor prior to treatment, and that women with low Par-4 levels in their primary tumors tend to respond less well to treatment and are more likely to experience a relapse. ...