Pennsylvania Sun news

No.1 draft pick signs with Pirates

THE PIRATES -- ONE OF THEIR FIRST ROUND DRAFT PICKS! REESE McGUIRE TURNS DOWN A SCHOLARSHIP TO THE UNIVERSITY OF SAN DIEGO TO BECOME A BUCCO. ACTION SPORTS GUY JUNKER -- CATCHING U TODAY WITH THE CATCHER OF TOMORROW! 3 3 3 ...
Okla. executes inmate convicted of killing couple

McALESTER, Okla. -- Oklahoma executed a 36-year-old man on Tuesday for the October 2000 stabbing deaths of a couple on whose ranch he had worked.James Lewis DeRosa was killed by lethal injection at the Oklahoma State Penitentiary in McAlester. He was the second inmate the state executed this year.Prosecutors say DeRosa and an accomplice, 33-year-old John Eric Castleberry, went to Curtis and ...
Ortiz Red Sox top Rays in rainy twinbill opener

Boston Red Sox's David Ortiz jogs off the field during a rain delay in the fifth inning of the first baseball game of a doubleheader against the Tampa Bay Rays in Boston, Tuesday, June 18, ...
Pa. Senate OKs bill to expand DNA tests in crimes

HARRISBURG, Pa. (AP) -- A bill to require DNA testing of suspects accused of certain crimes in Pennsylvania is headed to the state House of Representatives for the second time in two ...
Allegheny County seeks gas drilling bids

County Executive Rich Fitzgerald says Tuesday that the county could get up to $700,000 a year in royalty payments for drilling under Deer Lake Park, which is about 20 miles northeast of Pittsburgh. There could also be a one-time signing bonus of $2 to $4 ...

Movie Review

Bad Education (La mala educación)

In Bad Education (La mala educacin), Pedro Almodvars deeply saturated noir/melodrama pastiche, past and present, fiction, and truth are so intertwined and turned around that any sense of mystery the film develops is ultimately subsumed by its incessant obsession with unkno ... ...

On Facebook

Southmoreland board plans vote on spending plan

The Southmoreland School District will vote on a final budget later this month with no expected real estate tax increase. On June 13, the board said the 2013-2014 school year will have expenditures set at $26,378,342 and revenues expected at $25,424,558, which would create a deficit of ...
Mt. Pleasant district has superintendent candidate

Robert Gumbita, board president, approached after the meeting, said the lawyer for the candidate for the position had not completed a review of the contract. Gumbita declined to name the candidate, adding no contract has been ...
Dawson residents learn ins outs of dog enforcement

Members of the Tri-Town Community Crime Watch met in Dawson with the dog enforcement warden for Fayette and Westmoreland counties to provide information and answer questions concerning dog ...
Connellsville Lions’ ‘Bike With Bud’s’ planned for Saturday

The second Lions "Bike With Bud's" -- a 16-mile bike ride and fundraiser from Connellsville to Camp Carmel along the scenic Great Allegheny Passage -- will be held on ...
Mt. Pleasant Community Yard Sale set for Saturday

Mt. Pleasant Community Yard Sale will be held Saturday. Anyone interested in selling or buying should plan to hit the borough's streets for some great shopping and treasure hunting. The yard sale will be held throughout the town and will begin at 8 a.m. Maps of the street addresses of many of the families who are participating will be available at the Cat Committee booth that will be set up ...

More Pennsylvania Sun news

Making headlines

Our nuclear programmes are completely transparent. But we are ready to show greater transparency and make clear for the whole world that the steps of the Islamic Republic of Iran are completely within international frameworks. The sanctions are unfair, the Iranian people are suffering, and our (nuclear) activities are legal. These sanctions are illegal and only benefit Israel.

Hassan Rouhani

Iran's president-elect was speaking after his historic election victory.

Hotel Review

Beach Rotana Hotel & Towers

I could not find the Web site for this hotel, and it was not listed on any of the Internet ...

Keep reading

Have Your Say

Should tax havens be forced to lift their shroud of secrecy?

Pennsylvania Sun

Pennsylvania Sun | Reporting the News in Pennsylvania

Every minute of every day our news editors canvass the issues, and stories making the news to provide our readers with a broad and in-depth coverage of what's happening in the world.

Our first priority is the state. We specialise in Pennsylvania news. From Pittsburgh to Philadelphia, we're on the lookout day and night to keep track of issues making the news. We also strive to keep abreast of national news.

Breaking stories out of the continental United States usually break first on the Pennsylvania Sun. Neighbouring states and key cities too often feature on our news pages.

We also provide a whole lot of other content you'd expect from any newspaper including international sports coverage and local Pennsylvania weather forecasts.

We also provide readers with an opportunity to engage in newsmaking by voting on major stories in the news, and following how other readers are viewing the issues. Our news polls are regularly updated, and attract thousands of voters over each week they're conducted.

Our business writers too work hard to keep you abreast of what's happening in the markets, not only in the U.S. but across the globe. We work around the clock to post stories from major financial centers like Tokyo, Paris, London, and of course New York, where we have extensive coverage of the major indices, particularly the Dow Jones, Nasdaq, S&P and Russell 2000.

Follow Pennsylvania Sun on Facebook

News Releases

The Pennsylvania Sun.com News Release Publishing Service provides a medium for circulating your organization's news.

U.S. Markets

Featured Story

Protein key to breast cancer recurrence identified

Researchers at the Perelman School of Medicine, University of Pennsylvania have identified a key molecular player in recurrent breast cancer - a finding that suggests potential new therapeutic strategies.

The study, performed in the laboratory of Lewis A. Chodosh MD, PhD, chair of Cancer Biology and director of Cancer Genetics at the Abramson Family Cancer Research Institute, implicates the tumor suppressor protein Par-4 in recurrent breast cancer.

Par-4 is downregulated in recurrent tumors, and knocking the gene's expression down accelerates tumor recurrence in a mouse model of recurrent breast cancer. Conversely, overexpressing Par-4 delays the onset of tumor recurrence.

Data from human breast cancer patients confirm these findings. The authors analyzed patient tumors from the I-SPY 1 TRIAL, a clinical trial that measured tumor gene expression patterns and response to neoadjuvant chemotherapy.

They found that Par-4 expression is low in "residual disease" (that portion of a tumor that survives chemotherapy) compared to the primary tumor prior to treatment, and that women with low Par-4 levels in their primary tumors tend to respond less well to treatment and are more likely to experience a relapse. ...